Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29049027 | 0.83 | MAPT (0.44) | KMT2AMAPTMEN1LMNAESR1 | |
| SCHEMBL30460852 | 0.83 | MAPT (0.44) | KMT2AMAPTMEN1LMNAESR1 | |
| SCHEMBL25277576 | 0.82 | KMT2A (0.38) | KMT2AMAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL25235050 | 0.80 | TDP1 (0.43) | KMT2AMAPTMEN1TDP1LMNA | |
| SCHEMBL29048993 | 0.78 | KMT2A (0.41) | KMT2AMAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL31164103 | 0.77 | NPC1 (0.40) | KMT2AMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL25271973 | 0.75 | SMN1; SMN2 (0.40) | KMT2AMAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL10656685 | 0.69 | KMT2A (0.48) | KMT2AMAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL25277385 | 0.68 | ABL1 (0.49) | KMT2ASMN1; SMN2KDM4EMEN1LMNA | |
| SCHEMBL27633082 | 0.68 | KMT2A (0.51) | KMT2AMAPTSMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354957-A | CDK9 inhibitors and uses thereof | 药捷安康(南京)科技股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| WO-2023109959-A1 | CDK9 INHIBITOR AND USE THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-06-22 | — | — | WO | disclosed |