Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25271973 | 0.81 | SMN1; SMN2 (0.40) | KMT2AMAPTHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL31164075 | 0.79 | NPC1 (0.36) | KMT2ASMN1; SMN2LMNAMEN1GRM5 | |
| SCHEMBL25277384 | 0.78 | KMT2A (0.42) | KMT2AMAPTHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL27548231 | 0.73 | PARP10 (0.54) | KMT2AMAPTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL27552383 | 0.72 | PARP10 (0.42) | KMT2AMAPTHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL27550238 | 0.68 | PARP10 (0.57) | KMT2AMAPTSMN1; SMN2MEN1TDP1 | |
| SCHEMBL28043724 | 0.68 | NUDT1 (0.61) | KMT2AMAPTHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL22557648 | 0.67 | KMT2A (0.47) | KMT2AMAPTHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL27633082 | 0.67 | KMT2A (0.51) | KMT2AMAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL9098390 | 0.67 | KMT2A (0.40) | KMT2AMAPTHPGDKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354957-A | CDK9 inhibitors and uses thereof | 药捷安康(南京)科技股份有限公司 | 2023-06-30 | — | — | CN | disclosed |