Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2528612 | 0.93 | BACE1 (0.39) | AOC3ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL2525566 | 0.91 | AOC3 (0.46) | AOC3BCHEBACE1L3MBTL1 | |
| SCHEMBL2526825 | 0.88 | AOC3 (0.46) | AOC3ALDH1A1HSD17B10NPSR1L3MBTL1 | |
| SCHEMBL2529628 | 0.84 | ELANE (0.42) | AOC3CYP2D6ELANEBCHEBACE1 | |
| SCHEMBL2527548 | 0.83 | KMT2A (0.46) | AOC3ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL2528096 | 0.82 | BACE1 (0.38) | AOC3MEN1KMT2ABACE1L3MBTL1 | |
| SCHEMBL2525142 | 0.81 | AOC3 (0.40) | AOC3HSD17B10SLC6A3CYP2D6ELANE | |
| SCHEMBL2529791 | 0.81 | BACE1 (0.38) | AOC3ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL2526823 | 0.81 | AOC3 (0.43) | AOC3ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL2528484 | 0.80 | AOC3 (0.42) | AOC3ALDH1A1NPSR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | disclosed |
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | HRH1, HRH3, HRH2 | AOC3 2105/4885ALDH1A1 3248/4885HSD17B10 1710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.