Deoxyguanosine Triphosphate

Deoxyguanosine Triphosphate

SCHEMBL252797

Nc1nc2c(ncn2[C@H]2CC(O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.81
P2RY2 P41231 2/20 0.74
P2RY4 P51582 2/20 0.74
P2RY6 Q15077 2/20 0.74
TGM2 P21980 1/20 0.60
FUT5 Q11128 1/20 0.60
KRAS P01116 2/20 0.59
POLG P54098 1/20 0.57
NT5E P21589 2/20 0.56
PNP P00491 1/20 0.55
DTYMK P23919 4/20 0.55
P2RX3 P56373 1/20 0.51
ENPP1 P22413 1/20 0.51
P2RY1 P47900 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16699229 1.00 POLB (0.81) POLBP2RY2P2RY4P2RY6TGM2
Deoxyguanosine Triphosphate SCHEMBL28008515 1.00 POLB (0.81) POLBP2RY2P2RY4P2RY6TGM2
Deoxyguanosine Triphosphate SCHEMBL13111568 1.00 POLB (0.81) POLBP2RY2P2RY4P2RY6TGM2
Deoxyguanosine Triphosphate SCHEMBL2820367 1.00 POLB (0.81) POLBP2RY2P2RY4P2RY6TGM2
SCHEMBL3042901 1.00 POLB (0.81) POLBP2RY2P2RY4P2RY6TGM2
Deoxyguanosine Triphosphate SCHEMBL80609 1.00 POLB (0.81) POLBP2RY2P2RY4P2RY6TGM2
Deoxyguanosine Triphosphate SCHEMBL18785123 1.00 POLB (0.81) POLBP2RY2P2RY4P2RY6TGM2
Deoxyguanosine Triphosphate SCHEMBL12729493 1.00 POLB (0.81) POLBP2RY2P2RY4P2RY6TGM2
Deoxyguanosine Triphosphate SCHEMBL4558366 0.99 POLB (0.80) POLBP2RY2P2RY4P2RY6TGM2
SCHEMBL18785152 0.99 POLB (0.82) POLBP2RY2P2RY4P2RY6TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 649 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072741-A1 PRESERVATIVES FOR MOLECULAR SAMPLE ANALYSIS WITH SAMPLE COLLECTION DEVICES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-04-03 WO claimed
US-20240076803-A1 Method for Library Preparation in Next Generation Sequencing by Enzymatic DNA Fragmentation Miltenyi Biotec B.V. & Co. KG (DE) 2024-03-07 US claimed
US-20230027906-A1 TERT Promoter Droplet Digital PCR Assay for the Diagnosis of Malignant Cancers THE GENERAL HOSPITAL CORPORATION 2023-01-26 US claimed
EP-4036248-A1 METHOD FOR LIBRARY PREPARATION IN NEXT GENERATION SEQUENCING BY ENZYMATIC DNA FRAGMENTATION Miltenyi Biotec B.V. & Co. KG (DE) 2022-08-03 EP claimed
US-10829812-B1 Amplification of oligonucleotides containing non-standard nucleotides NATIONAL SCIENCE FOUNDATION 2020-11-10 US claimed
US-7794936-B1 Using thymidine analogs to improve replication in an expanded genetic alphabet BENNER STEVEN ALBERT 2010-09-14 US claimed
US-20090233280-A1 METHOD OF ACQUIRING INFORMATION REGARDING BASE SEQUENCE AND INFORMATION READING DEVICE FOR THE SAME CANON KABUSHIKI KAISHA (JP) 2009-09-17 US claimed
EP-1590484-B1 METHOD FOR THE DETECTION OF CYTOSINE METHYLATION PATTERNS WITH HIGH SENSITIVITY EPIGENOMICS AG (DE) 2009-08-19 EP claimed
US-20060263779-A1 Method for the detection of cytosine methylation patterns with high sensitivity EPIGENOMICS AG (DE) 2006-11-23 US claimed
EP-1192720-B1 ANCHORED STRAND DISPLACEMENT AMPLIFICATION ON AN ELECTRONICALLY ADDRESSABLE MICROCHIP NANOGEN BECTON DICKINSON PARTN (US) 2006-08-09 EP claimed
US-6531302-B1 Using primer pair sets anchored to a microarray through capture sites or through a branched primer pair moiety; allows for simultaneous multiplex capture, amplification, and detection of a target nucleic acid NANOGEN/BECTON DICKINSON PARTNERSHIP 2003-03-11 US claimed
US-6340747-B1 COMPLEXED TO RARE EARTH METAL CRYPTATE LABEL; DETECTION AND ISOLATION OF NUCLEIC ACIDS CIS BIO INTERNATIONAL (FR) 2002-01-22 US claimed
JP-2001518281-A 2001-10-16 JP claimed
US-6103487-A DETECTING MODULATORS THAT SUPPRESS THE ACTIVITY OF A TRANSFERASES; ANTICARCINOGENIC AGENTS MERCK & CO., INC. (US) 2000-08-15 US claimed
EP-1019530-A1 A METHOD OF TREATING CANCER Merck & Co., Inc. (US) 2000-07-19 EP claimed
EP-1009854-A1 A METHOD OF TREATING CANCER Merck & Co., Inc. (US) 2000-06-21 EP claimed
US-6063604-A SEPARATION OF TARGET NUCLEOTIDE SEQUENCE FOUND WITHIN A SINGLE-STRANDED POLYNUCLEOTIDE; PROVIDING A REACTION MIXTURE, SEPARATING NUCLEOTIDE SEQUENCES, ALLOWING HYBRIDIZATION, PRIMER EXTENSION AND BREAKING, AMPLIFY NUCLEOTIDES MOLECULAR BIOLOGY RESOURCES, INC. (US) 2000-05-16 US claimed
WO-1999010523-A1 A METHOD OF TREATING CANCER MERCK & CO., INC. (US) 1999-03-04 WO claimed
WO-1999010524-A1 A METHOD OF TREATING CANCER MERCK & CO., INC. (US) 1999-03-04 WO claimed
US-4804748-A DNA SEQUENCING BOEHRINGER MANNHEIM GMBH (DE) 1989-02-14 US claimed