Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25691607 | 1.00 | GAA (0.65) | GAALMNARECQLRAB9ADGAT1 | |
| SCHEMBL25043193 | 0.88 | LMNA (0.57) | GAALMNARECQLRAB9ADGAT1 | |
| SCHEMBL30051056 | 0.84 | GAA (0.68) | GAALMNARECQLRAB9ATDP1 | |
| SCHEMBL3490146 | 0.84 | GAA (0.68) | GAALMNARECQLRAB9ATDP1 | |
| SCHEMBL2846957 | 0.84 | GAA (0.68) | GAALMNARECQLRAB9ATDP1 | |
| SCHEMBL29246709 | 0.84 | RECQL (0.60) | GAALMNARECQLRAB9ATDP1 | |
| SCHEMBL30963324 | 0.83 | RECQL (0.58) | GAALMNARECQLRAB9ACYP1A2 | |
| SCHEMBL2066285 | 0.83 | RECQL (0.58) | GAALMNARECQLRAB9ACYP1A2 | |
| SCHEMBL2066283 | 0.83 | RECQL (0.58) | GAALMNARECQLRAB9ACYP1A2 | |
| SCHEMBL15219123 | 0.83 | LMNA (0.63) | GAALMNARECQLRAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192680-A1 | NEW AGENT FOR PROMOTING PHOSPHORYLATION OF eIF2a | ER STRESS RESEARCH INSTITUTE, INC. (JP) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192680-A1 | NEW AGENT FOR PROMOTING PHOSPHORYLATION OF eIF2a | EIF2A, EIF2AK1, EIF2AK4 | GAA 3607/4885LMNA 3348/4885RECQL 2478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.