Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 17/20 | 0.49 |
| ▸ | TYK2 | P29597 | 5/20 | 0.44 |
| ▸ | JAK3 | P52333 | 5/20 | 0.44 |
| ▸ | JAK2 | O60674 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 3/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25280432 | 1.00 | JAK1 (0.49) | JAK1TYK2JAK3JAK2CYP3A4 | |
| SCHEMBL30480407 | 1.00 | JAK1 (0.49) | JAK1TYK2JAK3JAK2CYP3A4 | |
| SCHEMBL30995746 | 0.93 | JAK1 (0.55) | JAK1TYK2JAK3JAK2CYP3A4 | |
| SCHEMBL25238208 | 0.92 | JAK1 (0.51) | JAK1TYK2JAK3JAK2CYP3A4 | |
| SCHEMBL30995740 | 0.92 | JAK1 (0.51) | JAK1TYK2JAK3JAK2CYP3A4 | |
| SCHEMBL30995742 | 0.91 | JAK1 (0.50) | JAK1TYK2JAK3JAK2CYP3A4 | |
| SCHEMBL25282348 | 0.88 | JAK1 (0.42) | JAK1TYK2JAK3JAK2CYP3A4 | |
| SCHEMBL29460494 | 0.88 | JAK1 (0.42) | JAK1TYK2JAK3JAK2CYP3A4 | |
| SCHEMBL25282349 | 0.88 | JAK1 (0.42) | JAK1TYK2JAK3JAK2CYP3A4 | |
| SCHEMBL30480457 | 0.88 | JAK1 (0.42) | JAK1TYK2JAK3JAK2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023115327-A1 | PYRIDO RING COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATE, COMPOSITION, AND APPLICATION | 中国药科大学 | 2023-06-29 | — | — | WO | disclosed |