Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 20/20 | 0.51 |
| ▸ | TYK2 | P29597 | 4/20 | 0.42 |
| ▸ | JAK3 | P52333 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 5/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25238208 | 1.00 | JAK1 (0.51) | JAK1TYK2JAK3CYP3A4KCNH2 | |
| SCHEMBL30995742 | 0.98 | JAK1 (0.50) | JAK1TYK2JAK3CYP3A4KCNH2 | |
| SCHEMBL30995746 | 0.96 | JAK1 (0.55) | JAK1TYK2JAK3CYP3A4KCNH2 | |
| SCHEMBL25280432 | 0.92 | JAK1 (0.49) | JAK1TYK2JAK3CYP3A4KCNH2 | |
| SCHEMBL25280431 | 0.92 | JAK1 (0.49) | JAK1TYK2JAK3CYP3A4KCNH2 | |
| SCHEMBL30480407 | 0.92 | JAK1 (0.49) | JAK1TYK2JAK3CYP3A4KCNH2 | |
| SCHEMBL29460508 | 0.91 | JAK1 (0.42) | JAK1TYK2JAK3CYP3A4JAK2 | |
| SCHEMBL25280077 | 0.89 | JAK1 (0.46) | JAK1TYK2JAK3CYP3A4KCNH2 | |
| SCHEMBL25280078 | 0.89 | JAK1 (0.46) | JAK1TYK2JAK3CYP3A4KCNH2 | |
| SCHEMBL30480431 | 0.89 | JAK1 (0.46) | JAK1TYK2JAK3CYP3A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393923-A1 | PYRIDO RING COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATE, COMPOSITION, AND APPLICATION | Yiyou Biotech (Shanghai) Co., Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |