Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RPA1 | P27694 | 3/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MARS1 | P56192 | 4/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10581947 | 0.88 | RPA1 (0.55) | RPA1NOTUMALDH1A1MARS1GABRA2 | |
| SCHEMBL25300050 | 0.82 | RPA1 (0.43) | HTTRPA1MARS1GABRA2GABRB2 | |
| SCHEMBL27934074 | 0.79 | KMT2A (0.41) | HTTNOTUMALDH1A1GABRA2GABRB2 | |
| SCHEMBL25238196 | 0.79 | GABRA2 (0.49) | NOTUMGABRA2GABRB2KDM4E | |
| SCHEMBL15754423 | 0.77 | RPA1 (0.50) | RPA1NOTUMALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9077378 | 0.76 | CLK1 (0.50) | ALDH1A1KDM4ESMN1; SMN2CASP1 | |
| SCHEMBL31587999 | 0.76 | POLB (0.58) | NOTUMALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL25232370 | 0.74 | S1PR4 (0.52) | HTTNOTUML3MBTL1SMN1; SMN2 | |
| SCHEMBL30630538 | 0.74 | CHRM4 (0.40) | LMNA | |
| SCHEMBL16202102 | 0.73 | MAPT (0.53) | HTTNOTUMALDH1A1TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114977-A1 | S1PR4 RECEPTOR ANTAGONISTS AND METHODS OF USE THEREOF | TIAKI THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |