⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14690544 | 0.78 | — | — | |
| SCHEMBL563796 | 0.76 | — | — | |
| SCHEMBL24453092 | 0.76 | — | — | |
| SCHEMBL11037641 | 0.66 | — | — | |
| SCHEMBL24805464 | 0.62 | — | — | |
| SCHEMBL14749839 | 0.62 | — | — | |
| SCHEMBL16118869 | 0.62 | — | — | |
| SCHEMBL761123 | 0.62 | — | — | |
| SCHEMBL437804 | 0.62 | — | — | |
| SCHEMBL1936620 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250059185-A1 | BICYCLIC HETEROCYCLIC COMPOUNDS USEFUL AS MONOACYLGLYCEROL LIPASE INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 2025-02-20 | — | — | US | disclosed |
| EP-4448522-A1 | BICYCLIC HETEROCYCLIC COMPOUNDS USEFUL AS MONOACYLGLYCEROL LIPASE INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2024-10-23 | — | — | EP | disclosed |
| CN-118488953-A | Bicyclic heterocyclic compounds useful as monoacylglycerol lipase inhibitors | 豪夫迈·罗氏有限公司 | 2024-08-13 | — | — | CN | disclosed |
| WO-2023110958-A1 | BICYCLIC HETEROCYCLIC COMPOUNDS USEFUL AS MONOACYLGLYCEROL LIPASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-06-22 | — | — | WO | disclosed |
| CN-115873000-A | Isoquinolone and quinazolinone compounds, and composition and application thereof | 中山医诺维申新药研发有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-111146497-B | Additive for battery electrolyte, lithium ion battery electrolyte and lithium ion battery | 深圳市比克动力电池有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-111146497-A | Additive for battery electrolyte, lithium ion battery electrolyte and lithium ion battery | 深圳市比克动力电池有限公司 | 2020-05-12 | — | — | CN | disclosed |