Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16882773 | 0.98 | KDM4E (0.47) | KDM4ESMN1; SMN2GPR84FFAR1FFAR4 | |
| SCHEMBL2530966 | 0.98 | KDM4E (0.47) | KDM4ESMN1; SMN2GPR84FFAR1FFAR4 | |
| SCHEMBL16882938 | 0.98 | KDM4E (0.47) | KDM4ESMN1; SMN2GPR84FFAR1FFAR4 | |
| SCHEMBL2528149 | 0.93 | CAMK2A (0.40) | KDM4ESMN1; SMN2CES2LTA4HMEN1 | |
| SCHEMBL3409269 | 0.84 | CES2 (0.56) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL2532287 | 0.83 | — | — | |
| SCHEMBL2527248 | 0.83 | SMN1; SMN2 (0.41) | KDM4ESMN1; SMN2GPR84FFAR1FFAR4 | |
| SCHEMBL20848102 | 0.82 | CES2 (0.43) | CES2LTA4HMEN1FAAHMAPK1 | |
| SCHEMBL21318254 | 0.82 | CES2 (0.59) | GPR84CES2MEN1FAAHMAPK1 | |
| SCHEMBL21448711 | 0.82 | CES2 (0.59) | GPR84CES2MEN1FAAHMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |
| EP-2441783-B1 | Lithographic printing plate precursor and lithographic printing method | FUJIFILM CORP (JP) | 2015-03-04 | — | — | EP | disclosed |
| US-4424343-A | Preparation of 1-N- ω-amino-α-hydroxyalkanoyl!kanamycin polysilylates and products | BRISTOL MYERS COMPANY (US) | 1984-01-03 | — | — | US | disclosed |