Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25789845 | 0.92 | CSNK2A1 (0.45) | TP53CSNK2A2CSNK2BCSNK2A1PIM1 | |
| SCHEMBL30486957 | 0.92 | CSNK2A1 (0.45) | TP53CSNK2A2CSNK2BCSNK2A1PIM1 | |
| SCHEMBL25290607 | 0.91 | CSNK2A1 (0.53) | TP53CSNK2A2CSNK2BCSNK2A1PIM1 | |
| SCHEMBL25789847 | 0.84 | CSNK2A1 (0.54) | CSNK2A2CSNK2BCSNK2A1PIM1PIM2 | |
| SCHEMBL30486986 | 0.84 | CSNK2A1 (0.54) | CSNK2A2CSNK2BCSNK2A1PIM1PIM2 | |
| SCHEMBL25288744 | 0.82 | CSNK2A1 (0.45) | TP53CSNK2A1GAAMAPTALDH1A1 | |
| SCHEMBL25243358 | 0.82 | CSNK2A1 (0.55) | CSNK2A2CSNK2BCSNK2A1PIM1PIM2 | |
| SCHEMBL25244888 | 0.81 | CSNK2A1 (0.44) | CSNK2A2CSNK2BCSNK2A1PIM1PIM2 | |
| SCHEMBL30487001 | 0.81 | DRD2 (0.48) | TP53CSNK2A2CSNK2BCSNK2A1GAA | |
| SCHEMBL25244617 | 0.81 | CSNK2A1 (0.44) | TP53CSNK2A1GAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023126951-A1 | INHIBITORS OF AUTOPHAGY-RELATED PROTEIN-PROTEIN INTERACTIONS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-07-06 | — | — | WO | disclosed |