Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 3/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.32 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25237637 | 1.00 | IRAK4 (0.39) | IRAK4PIM1GHSRPTPN11HDAC1 | |
| SCHEMBL25278655 | 0.87 | HDAC1 (0.35) | IRAK4PIM1GHSRPTPN11HDAC1 | |
| SCHEMBL25240746 | 0.87 | GHSR (0.37) | PIM1GHSRPTPN11HDAC1PRKCQ | |
| SCHEMBL25284225 | 0.87 | GHSR (0.37) | PIM1GHSRPTPN11HDAC1PRKCQ | |
| SCHEMBL25237145 | 0.85 | PTPN11 (0.38) | IRAK4PIM1GHSRPTPN11HDAC1 | |
| SCHEMBL25237071 | 0.85 | PTPN11 (0.38) | IRAK4PIM1GHSRPTPN11HDAC1 | |
| Hydrochloric Acid SCHEMBL25283147 | 0.83 | PTPN11 (0.37) | IRAK4PIM1GHSRPTPN11HDAC1 | |
| SCHEMBL25284925 | 0.81 | HDAC1 (0.35) | IRAK4PIM1GHSRHDAC1PRKCQ | |
| SCHEMBL25234344 | 0.74 | PTPN11 (0.38) | IRAK4PIM1GHSRPTPN11HDAC1 | |
| SCHEMBL522830 | 0.72 | IRAK4 (0.40) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023110843-A1 | HETEROBICYCLIC DERIVATIVES AS ITK INHIBITORS | ALMIRALL, S.A. (ES) | 2023-06-22 | — | — | WO | disclosed |