Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22413321 | 1.00 | ATM (0.34) | ATMMMP2ANPEPGABRR1 | |
| SCHEMBL18957295 | 1.00 | ATM (0.34) | ATMMMP2ANPEPGABRR1 | |
| SCHEMBL18957397 | 1.00 | ATM (0.34) | ATMMMP2ANPEPGABRR1 | |
| SCHEMBL18956934 | 1.00 | ATM (0.34) | ATMMMP2ANPEPGABRR1 | |
| Hydrochloric Acid SCHEMBL18940606 | 0.98 | ATM (0.33) | ATMMMP2ANPEPGABRR1 | |
| SCHEMBL19815798 | 0.86 | GABRR1 (0.36) | MMP2ANPEPGABRR1 | |
| SCHEMBL29105801 | 0.84 | ATM (0.40) | ATM | |
| SCHEMBL29105799 | 0.84 | ATM (0.40) | ATM | |
| SCHEMBL1907444 | 0.81 | — | — | |
| SCHEMBL24076949 | 0.81 | CHRNB2 (0.47) | ATMMMP2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203010-A1 | BICYCLIC AMINE CDK12 INHIBITORS | INCYTE CORPORATION | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203010-A1 | BICYCLIC AMINE CDK12 INHIBITORS | CDK12, CDK1, CDK2 | ATM 135/4885MMP2 2179/4885ANPEP 2341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.