Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.67 |
| ▸ | BACE1 | P56817 | 1/20 | 0.67 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.66 |
| ▸ | F3 | P13726 | 2/20 | 0.66 |
| ▸ | MAOA | P21397 | 2/20 | 0.66 |
| ▸ | MAOB | P27338 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.66 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | P4HB | P07237 | 4/20 | 0.63 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25193875 | 1.00 | ESR1 (0.67) | ESR1ESR2BACE1CYP1B1F3 | |
| SCHEMBL29406397 | 1.00 | ESR1 (0.67) | ESR1ESR2BACE1CYP1B1F3 | |
| SCHEMBL31233016 | 1.00 | ESR1 (0.67) | ESR1ESR2BACE1CYP1B1F3 | |
| SCHEMBL1801640 | 0.90 | CYP1B1 (0.73) | ESR1ESR2CYP1B1MAOAMAOB | |
| SCHEMBL1801639 | 0.90 | CYP1B1 (0.73) | ESR1ESR2CYP1B1MAOAMAOB | |
| SCHEMBL25193892 | 0.89 | KMT2A (0.77) | ESR1ESR2CYP1B1F3MAOA | |
| SCHEMBL8735847 | 0.87 | CYP1B1 (0.68) | CYP1B1MAOAMAOBCYP3A4KMT2A | |
| SCHEMBL5873207 | 0.87 | CYP1B1 (0.68) | CYP1B1MAOAMAOBCYP3A4KMT2A | |
| SCHEMBL5873205 | 0.87 | CYP1B1 (0.68) | CYP1B1MAOAMAOBCYP3A4KMT2A | |
| SCHEMBL10616441 | 0.86 | CYP1B1 (0.67) | CYP1B1MAOAMAOBCYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260014100-A1 | Compositions and Methods for Treating Bleeding and Bleeding Disorders | YEWSAVIN INC (US) | 2026-01-15 | — | — | US | disclosed |
| US-12343317-B2 | Compositions and methods for treating bleeding and bleeding disorders | YewSavin, Inc. (US) | 2025-07-01 | — | — | US | disclosed |
| CN-116217461-B | Chalcone derivative containing indole structure and preparation method and application thereof | 贵州大学 | 2024-10-18 | — | — | CN | disclosed |
| CN-117343024-A | Chalcone derivative containing benzoxazole structure and preparation method and application thereof | 贵州大学 | 2024-01-05 | — | — | CN | disclosed |
| US-20230190679-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-06-22 | — | — | US | disclosed |
| CN-116217461-A | Chalcone derivative containing indole structure and preparation method and application thereof | 贵州大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-114085199-B | Chalcone derivative containing sulfonyl piperazine as well as preparation method and application thereof | 贵州大学 | 2023-04-21 | — | — | CN | disclosed |
| CN-109293616-B | Coumarin-containing chalcone derivatives, and preparation method and application thereof | 贵州大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-114085199-A | Chalcone derivative containing sulfonyl piperazine and preparation method and application thereof | 贵州大学 | 2022-02-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260014100-A1 | Compositions and Methods for Treating Bleeding and Bleeding Disorders | SERPINC1, F2, F13B | ESR1 2661/4885ESR2 3093/4885BACE1 712/4885 |
| US-20230190679-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | SERPINC1, SERPINE1, SERPINH1 | ESR1 3467/4885ESR2 3035/4885BACE1 1486/4885 |
| US-12343317-B2 | Compositions and methods for treating bleeding and bleeding disorders | SERPINC1, SERPINE1, SERPINH1 | ESR1 3467/4885ESR2 3035/4885BACE1 1486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.