Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 18/20 | 0.50 |
| ▸ | JAK1 | P23458 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25244650 | 0.85 | TYK2 (0.59) | TYK2JAK1POLBGAA | |
| SCHEMBL25288885 | 0.85 | POLB (0.48) | TYK2JAK1POLBGAA | |
| SCHEMBL26523189 | 0.85 | TYK2 (0.54) | TYK2JAK1CYP2C19 | |
| SCHEMBL25239536 | 0.83 | TYK2 (0.47) | TYK2JAK1POLBGAA | |
| SCHEMBL25248111 | 0.82 | TYK2 (0.65) | TYK2JAK1POLBGAA | |
| SCHEMBL25289314 | 0.82 | TYK2 (0.69) | TYK2JAK1 | |
| SCHEMBL25242554 | 0.82 | POLB (0.47) | TYK2JAK1POLBGAA | |
| SCHEMBL25242518 | 0.81 | TYK2 (0.55) | TYK2JAK1 | |
| SCHEMBL25242508 | 0.81 | TYK2 (0.47) | TYK2JAK1POLBGAA | |
| SCHEMBL25288507 | 0.81 | POLB (0.46) | TYK2JAK1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | claimed |
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | disclosed |