Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 4/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25285287 | 1.00 | CTSL (0.53) | CTSLSYKPPARAMAPTKLK7 | |
| SCHEMBL25243646 | 0.92 | CTSL (0.52) | CTSLSYKPPARAMAPTITGB3 | |
| SCHEMBL25283470 | 0.92 | CTSL (0.52) | CTSLSYKPPARAMAPTITGB3 | |
| SCHEMBL4510998 | 0.81 | CTSL (0.48) | CTSLSYKPPARAMAPTKMT2A | |
| SCHEMBL4511000 | 0.81 | CTSL (0.48) | CTSLSYKPPARAMAPTKMT2A | |
| SCHEMBL18215182 | 0.81 | HDAC4 (0.48) | CTSLKMT2AMEN1CTSS | |
| SCHEMBL28650985 | 0.81 | HDAC4 (0.48) | CTSLKMT2AMEN1CTSS | |
| SCHEMBL16732549 | 0.78 | CTSL (0.52) | CTSLSYKPPARAMAPTKLK7 | |
| SCHEMBL16732553 | 0.78 | CTSL (0.52) | CTSLSYKPPARAMAPTKLK7 | |
| SCHEMBL25282355 | 0.78 | HPGD (0.48) | HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116824-A1 | PYRIDAZINONE COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION THEREOF | 中国药科大学 | 2023-06-29 | — | — | WO | disclosed |