Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 13/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25244580 | 0.86 | TYK2 (0.42) | TYK2 | |
| SCHEMBL25289687 | 0.81 | TYK2 (0.42) | TYK2 | |
| SCHEMBL25250500 | 0.80 | TYK2 (0.52) | TYK2 | |
| SCHEMBL25292409 | 0.78 | TYK2 (0.52) | TYK2 | |
| SCHEMBL25244500 | 0.78 | TYK2 (0.53) | TYK2 | |
| SCHEMBL25242771 | 0.78 | TYK2 (0.50) | TYK2 | |
| SCHEMBL25242072 | 0.77 | TYK2 (0.47) | TYK2 | |
| SCHEMBL25243602 | 0.77 | TYK2 (0.49) | TYK2 | |
| SCHEMBL25247291 | 0.77 | TYK2 (0.44) | TYK2 | |
| SCHEMBL25243819 | 0.77 | TYK2 (0.66) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | claimed |
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | disclosed |