Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | ACR | P10323 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | PPARD | Q03181 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2528596 | 1.00 | ALDH1A1 (0.42) | ALDH1A1PKMKMT2AMAPTL3MBTL1 | |
| SCHEMBL2525241 | 0.91 | KMT2A (0.51) | ALDH1A1PKMKMT2AMAPTL3MBTL1 | |
| SCHEMBL2531804 | 0.89 | ALDH1A1 (0.44) | ALDH1A1PKMKMT2AMAPTL3MBTL1 | |
| SCHEMBL2532097 | 0.84 | AOC3 (0.42) | ALDH1A1PKMKMT2AMAPTSLC6A2 | |
| SCHEMBL2525522 | 0.84 | MAPT (0.49) | ALDH1A1PKMKMT2AMAPTL3MBTL1 | |
| SCHEMBL2529638 | 0.84 | KMT2A (0.41) | ALDH1A1PKMKMT2AMAPTL3MBTL1 | |
| SCHEMBL2531521 | 0.84 | SLC6A2 (0.39) | ALDH1A1PKMKMT2AMAPTL3MBTL1 | |
| SCHEMBL2525770 | 0.84 | KMT2A (0.43) | ALDH1A1PKMKMT2AMAPTL3MBTL1 | |
| SCHEMBL2529170 | 0.82 | SLC6A2 (0.37) | ALDH1A1PKMKMT2AMAPTL3MBTL1 | |
| SCHEMBL2528590 | 0.82 | MAPT (0.41) | ALDH1A1PKMKMT2AMAPTCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | disclosed |
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | HRH1, HRH3, HRH2 | ALDH1A1 3248/4885PKM 3604/4885KMT2A 2317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.