Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 15/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 11/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 11/20 | 0.49 |
| ▸ | PIM1 | P11309 | 2/20 | 0.49 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.49 |
| ▸ | CSNK2A3 | Q8NEV1 | 7/20 | 0.48 |
| ▸ | CLK2 | P49760 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | GAK | O14976 | 1/20 | 0.48 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.48 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.48 |
| ▸ | ULK1 | O75385 | 1/20 | 0.48 |
| ▸ | STK10 | O94804 | 1/20 | 0.48 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25284487 | 0.87 | CSNK2A1 (0.50) | CSNK2A1CSNK2A2CSNK2BPIM1PIM2 | |
| SCHEMBL25246517 | 0.82 | CSNK2A2 (0.48) | CSNK2A1CSNK2A2CSNK2BPIM1PIM2 | |
| SCHEMBL25248131 | 0.80 | HDAC3 (0.52) | CSNK2A1CSNK2A2CSNK2BPIM1PIM2 | |
| SCHEMBL25286410 | 0.79 | CSNK2A1 (0.64) | CSNK2A1CSNK2A2CSNK2BPIM1PIM2 | |
| SCHEMBL25245825 | 0.78 | CSNK2A1 (0.58) | CSNK2A1CSNK2A2CSNK2BPIM1PIM2 | |
| SCHEMBL25293867 | 0.77 | CSNK2A1 (0.52) | CSNK2A1CSNK2A2CSNK2BMAPT | |
| SCHEMBL2689292 | 0.77 | CSNK2A1 (0.80) | CSNK2A1CSNK2A2CSNK2BPIM1PIM2 | |
| SCHEMBL30486966 | 0.77 | CSNK2A1 (0.73) | CSNK2A1CSNK2A2CSNK2BPIM1PIM2 | |
| SCHEMBL25247670 | 0.77 | CSNK2A1 (0.73) | CSNK2A1CSNK2A2CSNK2BPIM1PIM2 | |
| SCHEMBL25239462 | 0.75 | CSNK2A1 (0.67) | CSNK2A1CSNK2A2CSNK2BPIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023126951-A1 | INHIBITORS OF AUTOPHAGY-RELATED PROTEIN-PROTEIN INTERACTIONS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-07-06 | — | — | WO | disclosed |
| WO-2023126951-A1 | INHIBITORS OF AUTOPHAGY-RELATED PROTEIN-PROTEIN INTERACTIONS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-07-06 | — | — | WO | disclosed |