Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3150356 | 0.72 | — | — | |
| SCHEMBL7938723 | 0.70 | MEN1 (0.33) | MEN1POLBKMT2A | |
| SCHEMBL2383002 | 0.69 | — | — | |
| SCHEMBL28014350 | 0.69 | MEN1 (0.32) | MEN1POLBKMT2A | |
| SCHEMBL10824758 | 0.69 | TSHR (0.35) | MEN1POLBKMT2A | |
| SCHEMBL10919175 | 0.69 | MEN1 (0.32) | MEN1POLBKMT2A | |
| SCHEMBL2142744 | 0.67 | — | — | |
| SCHEMBL2479662 | 0.67 | MEN1 (0.35) | MEN1POLBKMT2A | |
| SCHEMBL3417372 | 0.67 | TSHR (0.31) | MEN1POLBKMT2A | |
| SCHEMBL5561602 | 0.65 | MEN1 (0.30) | MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122760-A1 | NOVEL LIPIDS FOR TRANSFECTION OF NUCLEIC ACIDS | THOMPSON, PATRICK R. | 2012-05-17 | — | — | US | disclosed |
| US-8034977-B2 | Lipids for transfection of nucleic acids | MOLECULAR TRANSFER, INC. (US) | 2011-10-11 | — | — | US | disclosed |
| US-20090215067-A1 | NOVEL LIPIDS FOR TRANSFECTION OF NUCLEIC ACIDS | MOLECULAR TRANSFER, INC. (US) | 2009-08-27 | — | — | US | disclosed |
| US-7531693-B2 | Lipids for transfection of nucleic acids | MOLECULAR TRANSFER, INC. (US) | 2009-05-12 | — | — | US | disclosed |
| EP-1628647-A4 | NOVEL LIPIDS FOR TRANSFECTION OF NUCLEIC ACIDS | MOLECULAR TRANSFER INC (US) | 2007-10-24 | — | — | EP | disclosed |
| EP-1628647-A2 | NOVEL LIPIDS FOR TRANSFECTION OF NUCLEIC ACIDS | Molecular Transfer, Inc. (US) | 2006-03-01 | — | — | EP | disclosed |
| US-20050014962-A1 | Novel lipids for transfection of nucleic acids | THOMPSON AND PATRICIA A THOMPSON AS TRUSTEES OF THE THOMPSON FAMILY TRUST DATED AUGUST 27 2002, JOHN D. | 2005-01-20 | — | — | US | disclosed |
| WO-2004105697-A2 | NOVEL LIPIDS FOR TRANSFECTION OF NUCLEIC ACIDS | MOLECULAR TRANSFER, INC. (US) | 2004-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014962-A1 | Novel lipids for transfection of nucleic acids | ABHD16A, MBOAT7, NPC1L1 | MEN1 2648/4885POLB 463/4885KMT2A 3361/4885 |
| US-20090215067-A1 | NOVEL LIPIDS FOR TRANSFECTION OF NUCLEIC ACIDS | ABHD16A, MBOAT7, NPC1L1 | MEN1 2648/4885POLB 463/4885KMT2A 3361/4885 |
| US-20120122760-A1 | NOVEL LIPIDS FOR TRANSFECTION OF NUCLEIC ACIDS | ABHD16A, MBOAT7, NPC1L1 | MEN1 2648/4885POLB 463/4885KMT2A 3361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.