Sugi Predict

Sugi Predict / Targets / MBOAT7

MBOAT7

Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7 · Q96N66 · MBOAT7 on Sugi Atlas →

0 patent compounds predicted against MBOAT7, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to MBOAT7 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Ambroxol as a Treatment for Parkinson's Disease Dementia PHASE2UNKNOWN
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides PHASE1COMPLETED
Combining Gene Variants to Improve Risk Prediction for Metabolic (Dysfunction)- Associated Fatty Liver Disease and Its Progression to Cirrhosis in Indian Individuals With Type 2 Diabetes nanCOMPLETED
RCDP Natural History Study nanUNKNOWN
Development of Biomarker for Development of Non-Alcoholic Steatohepatitis (NASH) in Children nanWITHDRAWN
Lifestyle Intervention in Fatty Liver (NAFLD) nanUNKNOWN
Enpowering Progression Risk of Cerebral Amyloid Angiopathy nanCOMPLETED
Effect of PNPLA3, TM6SF2 and MBOAT7 Genetic Variants on Non-alcoholic Fatty Liver Disease Therapeutic Outcome. nanCOMPLETED
Registry Gangliosidoses nanUNKNOWN
Epidemiology of Atherosclerosis nanCOMPLETED
Genes Involved in Lipid Disorders nanCOMPLETED
Genomic Dissection of a QTL Affecting the Lipid Profile nanWITHDRAWN
Genetic Origin of Lipid Disorders nanUNKNOWN
LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies nanCOMPLETED
Biomarker for Mucolipidosis Disorder Type I, II, III, IV (BioML) nanWITHDRAWN
Structural Network on Prostate Cancer in the French Greater West Region nanCOMPLETED
Physiopathology of Pulmonary Arterial Hypertension: Mechanistic Studies nanUNKNOWN
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes nanCOMPLETED
The Classification and Cause of Leukodystrophies of Unknown Cause nanCOMPLETED
Identification of a New Gene Involved in Hereditary Lipodystrophy nanCOMPLETED
Fatty Acid Oxidation Defects and Insulin Sensitivity nanCOMPLETED
Familial Partial Lipodystrophy Study nanCOMPLETED
Phenotypic and Genotypic Studies in Congenital and Early Onset Ataxias nanCOMPLETED
The LD Lync Study - Natural History Study of Lipodystrophy Syndromes nanRECRUITING
FFAR Agonist on Incretins, Insulin, Lipids and Inflammation nanCOMPLETED
Effect of Omega-3 Fatty Acids Supplementation on Hypertriglyceridemia in Pediatric Patients With Obesity. nanCOMPLETED
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Study of Chediak-Higashi Syndrome nanRECRUITING
Immune Cell Response to Stimuli nanRECRUITING
Lipidomic and Multi-Omics Profiling of Fatty Liver Disease in People With and Without HIV nanNOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a MBOAT7 binder may also engage these)

ProteinNameSimilarity
Q0VCY6 — 1.000 Q0VCY6 →
Q8CHK3 — 0.999 Q8CHK3 →
Q8BMT9 — 0.962 Q8BMT9 →
HHAT Protein-cysteine N-palmitoyltransferase HHAT 0.961 landscape →
PORCN Protein-serine O-palmitoleoyltransferase porcupine 0.950 landscape →
Q9JJJ7 — 0.929 Q9JJJ7 →
P27544 — 0.924 P27544 →
Q58CT4 — 0.922 Q58CT4 →
Q6PDE8 — 0.921 Q6PDE8 →
Q9Y6C5 — 0.920 Q9Y6C5 →
Q0P5C0 — 0.920 Q0P5C0 →
P59266 — 0.920 P59266 →
Q14CX5 — 0.918 Q14CX5 →
D3ZVU9 — 0.918 D3ZVU9 →
Q6TCG5 — 0.918 Q6TCG5 →
O35595 — 0.917 O35595 →
Q148K5 — 0.917 Q148K5 →
Q96S06 — 0.916 Q96S06 →
Q5RFI0 — 0.915 Q5RFI0 →
Q9BSA9 — 0.915 Q9BSA9 →
Q6TCH4 — 0.915 Q6TCH4 →
Q3UGX3 — 0.915 Q3UGX3 →
Q96GM1 — 0.914 Q96GM1 →
Q6W5G4 — 0.914 Q6W5G4 →
B2LYG4 — 0.914 B2LYG4 →
Q8VCY8 — 0.914 Q8VCY8 →
Q2TBS1 — 0.914 Q2TBS1 →
Q4R3I0 — 0.914 Q4R3I0 →
Q5SUV1 — 0.913 Q5SUV1 →
O96011 — 0.913 O96011 →