Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.34 |
| ▸ | ACACB | O00763 | 4/20 | 0.32 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25288327 | 1.00 | GHSR (0.34) | GHSRACACBEIF2AK4PIM1HDAC1 | |
| SCHEMBL25288326 | 1.00 | GHSR (0.34) | GHSRACACBEIF2AK4PIM1HDAC1 | |
| SCHEMBL30457381 | 1.00 | GHSR (0.34) | GHSRACACBEIF2AK4PIM1HDAC1 | |
| SCHEMBL25243476 | 0.78 | CYP1A2 (0.33) | GHSRACACBHDAC1 | |
| SCHEMBL25237145 | 0.75 | PTPN11 (0.38) | GHSREIF2AK4PIM1HDAC1TLR9 | |
| SCHEMBL25237071 | 0.75 | PTPN11 (0.38) | GHSREIF2AK4PIM1HDAC1TLR9 | |
| Hydrochloric Acid SCHEMBL25283147 | 0.74 | PTPN11 (0.37) | GHSREIF2AK4PIM1HDAC1TLR9 | |
| SCHEMBL25285206 | 0.73 | KCNB1 (0.33) | — | |
| SCHEMBL25242681 | 0.73 | KCNB1 (0.33) | — | |
| SCHEMBL25285205 | 0.73 | KCNB1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023110843-A1 | HETEROBICYCLIC DERIVATIVES AS ITK INHIBITORS | ALMIRALL, S.A. (ES) | 2023-06-22 | — | — | WO | disclosed |