Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.61 |
| ▸ | CTSL | P07711 | 4/20 | 0.61 |
| ▸ | CTSB | P07858 | 4/20 | 0.61 |
| ▸ | CTSS | P25774 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25244521 | 1.00 | MEN1 (0.61) | MEN1KMT2ARCE1CTSLCTSB | |
| SCHEMBL24029390 | 0.89 | MEN1 (0.62) | MEN1KMT2ARCE1CTSLCTSB | |
| SCHEMBL25518572 | 0.89 | MEN1 (0.67) | MEN1KMT2ARCE1CTSLCTSB | |
| SCHEMBL30174831 | 0.89 | MEN1 (0.67) | MEN1KMT2ARCE1CTSLCTSB | |
| SCHEMBL29393963 | 0.89 | MEN1 (0.67) | MEN1KMT2ARCE1CTSLCTSB | |
| SCHEMBL23824277 | 0.89 | MEN1 (0.67) | MEN1KMT2ARCE1CTSLCTSB | |
| SCHEMBL23824273 | 0.89 | MEN1 (0.67) | MEN1KMT2ARCE1CTSLCTSB | |
| SCHEMBL25837527 | 0.88 | CTSL (0.62) | MEN1KMT2ARCE1CTSLCTSB | |
| SCHEMBL25286907 | 0.88 | MEN1 (0.61) | MEN1KMT2ARCE1CTSLCTSB | |
| SCHEMBL25286906 | 0.88 | MEN1 (0.61) | MEN1KMT2ARCE1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204393-A1 | AMINOCARBAMOYL COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTIONS | F. Hoffmann-La Roche AG (CH) | 2023-07-05 | — | — | EP | disclosed |