Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.61 |
| ▸ | CTSB | P07858 | 4/20 | 0.61 |
| ▸ | CTSS | P25774 | 3/20 | 0.61 |
| ▸ | CTSL | P07711 | 3/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.48 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25242994 | 1.00 | CTSK (0.61) | CTSKCTSBCTSSCTSLCASP1 | |
| SCHEMBL25247153 | 0.99 | CTSK (0.63) | CTSKCTSBCTSSCTSLCASP1 | |
| SCHEMBL25286871 | 0.99 | CTSK (0.63) | CTSKCTSBCTSSCTSLCASP1 | |
| Hydrochloric Acid SCHEMBL25288896 | 0.94 | CTSK (0.54) | CTSKCTSBCTSSCTSLTACR1 | |
| Hydrochloric Acid SCHEMBL25288895 | 0.94 | CTSK (0.54) | CTSKCTSBCTSSCTSLTACR1 | |
| SCHEMBL25282430 | 0.89 | CTSK (0.65) | CTSKCTSBCTSSCTSLCASP1 | |
| SCHEMBL25282429 | 0.89 | CTSK (0.65) | CTSKCTSBCTSSCTSLCASP1 | |
| SCHEMBL25290639 | 0.88 | CTSK (0.61) | CTSKCTSBCTSSCTSLCASP1 | |
| SCHEMBL25290638 | 0.88 | CTSK (0.61) | CTSKCTSBCTSSCTSLCASP1 | |
| SCHEMBL4622697 | 0.88 | CTSK (0.67) | CTSKCTSBCTSSCTSLCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116438160-A | Carbamoyl compounds for the treatment of viral infections | 豪夫迈·罗氏有限公司 | 2023-07-14 | — | — | CN | disclosed |
| EP-4204393-A1 | AMINOCARBAMOYL COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTIONS | F. Hoffmann-La Roche AG (CH) | 2023-07-05 | — | — | EP | disclosed |
| WO-2022043374-A1 | AMINOCARBAMOYL COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTIONS | F. HOFFMANN-LA ROCHE AG (CH) | 2022-03-03 | — | — | WO | disclosed |