Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 6/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25242302 | 0.86 | RIPK1 (0.39) | RIPK1GRM5SLC6A2SLC6A4MEN1 | |
| SCHEMBL5651229 | 0.81 | RIPK1 (0.42) | RIPK1GRM5SLC6A2SLC6A4MEN1 | |
| SCHEMBL5647255 | 0.80 | RIPK1 (0.41) | RIPK1GRM5SLC6A2SLC6A4MEN1 | |
| SCHEMBL25286605 | 0.79 | RIPK1 (0.34) | RIPK1GRM5SLC6A2SLC6A4 | |
| SCHEMBL25242324 | 0.78 | RIPK1 (0.37) | RIPK1GRM5SLC6A2SLC6A4MEN1 | |
| SCHEMBL25286462 | 0.77 | RIPK1 (0.36) | RIPK1GRM5SLC6A2SLC6A4MEN1 | |
| SCHEMBL5648402 | 0.76 | RIPK1 (0.38) | RIPK1GRM5SLC6A2SLC6A4MEN1 | |
| SCHEMBL3754160 | 0.75 | KCNA5 (0.41) | RIPK1LMNAALDH1A1 | |
| SCHEMBL1438626 | 0.68 | RIPK1 (0.41) | RIPK1MEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL2518672 | 0.67 | MEN1 (0.38) | RIPK1MEN1KMT2AHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125935-A1 | BENZOPYRIDINE DERIVATIVE REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |