Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15282217 | 0.81 | MEN1 (0.32) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL20530413 | 0.80 | LMNA (0.39) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL25831757 | 0.77 | LMNA (0.40) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL24253819 | 0.76 | LMNA (0.39) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL3964300 | 0.75 | LMNA (0.42) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL25386450 | 0.75 | TSHR (0.40) | FFAR1CPT2TDP1 | |
| SCHEMBL1975814 | 0.75 | TSHR (0.40) | FFAR1CPT2TDP1 | |
| SCHEMBL25384997 | 0.75 | TSHR (0.40) | FFAR1CPT2TDP1 | |
| SCHEMBL8618138 | 0.75 | MEN1 (0.44) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL23236462 | 0.75 | TSHR (0.40) | FFAR1CPT2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116934-A1 | KRASG12D PROTEIN HYDROLYSIS REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州泽璟生物制药股份有限公司 | 2023-06-29 | — | — | WO | disclosed |
| CN-116332959-A | KRAS G12D Proteolytic regulator and its prepn and application | 苏州泽璟生物制药股份有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-115043817-A | SOS1 proteolysis regulator and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2022-09-13 | — | — | CN | disclosed |