SCHEMBL25292249

SCHEMBL25292249

COc1ccccc1Nc1ccc(Cc2ccc(Nc3ccccc3OC)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 8/20 0.67
▸ ALDH1A1 P00352 4/20 0.67
▸ MAPK1 P28482 3/20 0.67
▸ L3MBTL1 Q9Y468 2/20 0.67
▸ KMT2A Q03164 5/20 0.55
▸ MEN1 O00255 4/20 0.55
▸ LMNA P02545 2/20 0.55
▸ GAA P10253 3/20 0.51
▸ RAB9A P51151 3/20 0.51
▸ NPC1 O15118 2/20 0.51
▸ POLB P06746 3/20 0.47
▸ KDM4E B2RXH2 3/20 0.46
▸ SMN1; SMN2 Q16637 2/20 0.46
▸ THRB P10828 2/20 0.46
▸ AURKA O14965 1/20 0.46
▸ MAPK10 P53779 2/20 0.45
▸ MAPK8 P45983 1/20 0.45
▸ MAPK14 Q16539 1/20 0.45
▸ LTA4H P09960 1/20 0.44
▸ HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5923796 0.89 MAPT (0.81) MAPTALDH1A1MAPK1L3MBTL1KMT2A
SCHEMBL1920776 0.83 MAPT (0.73) MAPTALDH1A1MAPK1L3MBTL1KMT2A
SCHEMBL2095055 0.83 MAPT (0.72) MAPTALDH1A1MAPK1L3MBTL1KMT2A
SCHEMBL29744518 0.83 MAPT (0.72) MAPTALDH1A1MAPK1L3MBTL1KMT2A
SCHEMBL17201829 0.81 MAPT (0.71) MAPTALDH1A1MAPK1L3MBTL1KMT2A
SCHEMBL15883217 0.81 ALDH1A1 (0.71) MAPTALDH1A1MAPK1L3MBTL1KMT2A
SCHEMBL30741238 0.81 MAPT (0.71) MAPTALDH1A1MAPK1L3MBTL1KMT2A
SCHEMBL10480096 0.81 MAPT (0.71) MAPTALDH1A1MAPK1L3MBTL1KMT2A
Hydrochloric Acid SCHEMBL7128944 0.81 MAPT (0.70) MAPTALDH1A1MAPK1L3MBTL1KMT2A
SCHEMBL28155954 0.80 MAPT (0.49) MAPTALDH1A1MAPK1L3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250084336-A1 COMPOUNDS AND LUBRICANT COMPOSITIONS CONTAINING THE SAME THE LUBRIZOL CORPORATION 2025-03-13 — — US disclosed
EP-4460550-A1 COMPOUNDS AND LUBRICANT COMPOSITIONS CONTAINING THE SAME The Lubrizol Corporation (US) 2024-11-13 — — EP disclosed
CN-118525074-A Compounds and lubricant compositions containing the same 路博润公司 2024-08-20 — — CN disclosed
WO-2023133090-A1 COMPOUNDS AND LUBRICANT COMPOSITIONS CONTAINING THE SAME THE LUBRIZOL CORPORATION (US) 2023-07-13 — — WO disclosed
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