Carbamic Acid

Carbamic Acid

SCHEMBL25294162

COC(=O)C1CO1.NC(=O)O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 1/20 0.38
PTPN1 P18031 1/20 0.38
PPP1CC P36873 1/20 0.38
PDK1 Q15118 1/20 0.38
MIF P14174 3/20 0.33
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CHRNB2 P17787 2/20 0.32
CHRNA4 P43681 2/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
ACHE P22303 1/20 0.32
HIF1A Q16665 1/20 0.32
MMP2 P08253 1/20 0.32
ANPEP P15144 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL839706 0.91
SCHEMBL839705 0.91
SCHEMBL30912051 0.91 PDK1 (0.42) PPM1BPTPN1PPP1CCPDK1MIF
SCHEMBL840388 0.91
Hydrochloric Acid SCHEMBL31256790 0.88
SCHEMBL28813625 0.88 PDK1 (0.41) PPM1BPTPN1PPP1CCPDK1MIF
SCHEMBL31571897 0.88 PDK1 (0.41) PPM1BPTPN1PPP1CCPDK1MIF
SCHEMBL3809389 0.88 PDK1 (0.41) PPM1BPTPN1PPP1CCPDK1MIF
SCHEMBL29199824 0.86 PPM1B (0.42) PPM1BPTPN1PPP1CCPDK1MIF
SCHEMBL29199825 0.86 PPM1B (0.42) PPM1BPTPN1PPP1CCPDK1MIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4223818-A1 EPOXY-URETHANE COMPOUNDS AND THEIR THERMOSETTING POLYMERS Covestro LLC (US) 2023-08-09 EP claimed
WO-2023114013-A1 EPOXY-URETHANE COMPOUNDS AND THEIR THERMOSETTING POLYMERS COVESTRO LLC (US) 2023-06-22 WO claimed
EP-4223818-A1 EPOXY-URETHANE COMPOUNDS AND THEIR THERMOSETTING POLYMERS Covestro LLC (US) 2023-08-09 EP disclosed
EP-4223818-A1 EPOXY-URETHANE COMPOUNDS AND THEIR THERMOSETTING POLYMERS Covestro LLC (US) 2023-08-09 EP disclosed
WO-2023114013-A1 EPOXY-URETHANE COMPOUNDS AND THEIR THERMOSETTING POLYMERS COVESTRO LLC (US) 2023-06-22 WO disclosed