Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIFC1 | Q9BW19 | 17/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25294382 | 0.91 | KIFC1 (0.71) | KIFC1DRD3 | |
| SCHEMBL25291474 | 0.88 | KIFC1 (0.71) | KIFC1DRD3 | |
| SCHEMBL25814238 | 0.83 | KIFC1 (0.42) | KIFC1 | |
| SCHEMBL25301296 | 0.80 | KIFC1 (0.39) | KIFC1 | |
| SCHEMBL30497248 | 0.79 | KIFC1 (0.66) | KIFC1DRD3 | |
| SCHEMBL25254978 | 0.79 | KIFC1 (0.66) | KIFC1DRD3 | |
| SCHEMBL25253800 | 0.79 | KIFC1 (0.82) | KIFC1 | |
| SCHEMBL25297805 | 0.77 | KIFC1 (0.84) | KIFC1DRD3S1PR1 | |
| SCHEMBL25262766 | 0.76 | KIFC1 (0.69) | KIFC1DRD3 | |
| SCHEMBL30497108 | 0.76 | KIFC1 (0.69) | KIFC1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250084074-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2025-03-13 | — | — | US | disclosed |
| EP-4463444-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | Merck Patent GmbH (DE) | 2024-11-20 | — | — | EP | disclosed |
| WO-2023131690-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2023-07-13 | — | — | WO | disclosed |
| WO-2023131690-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2023-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250084074-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | VHL, CDKN1A, CCNI | KIFC1 3173/4885DRD3 4812/4885S1PR1 1941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.