Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | MLNR | O43193 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | XIAP | P98170 | 2/20 | 0.31 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25295511 | 1.00 | CNR2 (0.40) | CNR2NTRK1CNR1MLNRCYP3A4 | |
| SCHEMBL25301086 | 0.90 | TMEM97 (0.37) | CNR2MLNRCYP3A4MEN1KMT2A | |
| SCHEMBL25301087 | 0.90 | TMEM97 (0.37) | CNR2MLNRCYP3A4MEN1KMT2A | |
| SCHEMBL25301094 | 0.89 | KMT2A (0.39) | CNR2NTRK1GRM2MEN1KMT2A | |
| SCHEMBL25301093 | 0.89 | KMT2A (0.39) | CNR2NTRK1GRM2MEN1KMT2A | |
| SCHEMBL25253586 | 0.89 | HRH4 (0.38) | CNR2NTRK1HTR2AHTR2CHSP90AA1 | |
| SCHEMBL25290408 | 0.89 | HRH4 (0.38) | CNR2NTRK1HTR2AHTR2CHSP90AA1 | |
| SCHEMBL25298378 | 0.86 | ADORA3 (0.35) | CNR2MLNRCYP3A4XIAPBIRC2 | |
| SCHEMBL25298379 | 0.86 | ADORA3 (0.35) | CNR2MLNRCYP3A4XIAPBIRC2 | |
| SCHEMBL25289846 | 0.86 | DPP4 (0.38) | CNR2MLNRCYP3A4KCNH2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12583866-B2 | Pyrido[2,3-b][1,4]oxazines or tetrahydropyrido[2,3-b][1,4]oxazepines as IAP antagonists | BEONE MEDICINES I GMBH (CH) | 2026-03-24 | — | — | US | disclosed |
| US-20230219975-A1 | PYRIDO[2,3-B][1,4]OXAZINES OR TETRAHYDROPYRIDO[2,3-B][1,4]OXAZEPINES AS IAP ANTAGONISTS | BEONE MEDICINES I GMBH (CH) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12583866-B2 | Pyrido[2,3-b][1,4]oxazines or tetrahydropyrido[2,3-b][1,4]oxazepines as IAP antagonists | BIRC2, BIRC3, BIRC5 | CNR2 2510/4885NTRK1 1577/4885CNR1 2501/4885 |
| US-20230219975-A1 | PYRIDO[2,3-B][1,4]OXAZINES OR TETRAHYDROPYRIDO[2,3-B][1,4]OXAZEPINES AS IAP ANTAGONISTS | BIRC2, BIRC3, API5 | CNR2 2424/4885NTRK1 2177/4885CNR1 1957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.