⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529651 | 1.00 | — | — | |
| SCHEMBL7424126 | 1.00 | — | — | |
| SCHEMBL713050 | 0.97 | — | — | |
| SCHEMBL712363 | 0.89 | — | — | |
| SCHEMBL12361992 | 0.86 | MAPK1 (0.35) | — | |
| SCHEMBL27240066 | 0.86 | MAPK1 (0.35) | — | |
| SCHEMBL19193963 | 0.86 | MAPK1 (0.35) | — | |
| SCHEMBL27240036 | 0.86 | MAPK1 (0.35) | — | |
| SCHEMBL26172972 | 0.86 | MAPK1 (0.35) | — | |
| SCHEMBL13538316 | 0.86 | MAPK1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |
| CN-116724040-A | Nitrogen-containing compounds for organic electroluminescent devices | 默克专利有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-110225752-B | Monocycles as GPR120 modulators | 整体健康 | 2023-05-05 | — | — | CN | disclosed |
| CN-115594673-A | Estrogen receptor modulators and uses thereof | 扬子江药业集团南京海陵药业有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-115210238-A | Substituted aminoquinolones as DGK alpha inhibitors for immune activation | 拜耳公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-109641182-B | Multilayer hollow fiber membrane | 杜邦安全与建筑公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-110785082-B | Compositions and methods comprising triarylpolyamines | 库扎环球有限责任公司 | 2021-12-28 | — | — | CN | disclosed |
| US-RE39088-E1 | Amide compounds and use of the same | JAPAN TOBACCO, INC. (JP) | 2006-05-02 | — | — | US | disclosed |
| WO-2005082459-A2 | METHOD OF DECREASING BLOOD CELLS | JAPAN TOBACCO INC. (JP) | 2005-09-09 | — | — | WO | disclosed |
| US-20050187221-A1 | Method of treating ischemia reperfusion injury | JAPAN TOBACCO INC. (JP) | 2005-08-25 | — | — | US | disclosed |
| EP-0891336-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-20 | — | — | EP | disclosed |
| CN-1189824-A | 1-amino-3-benzyluracils | BASF AG (DE) | 1998-08-05 | — | — | CN | disclosed |
| EP-0849256-A1 | AMIDE COMPOUNDS AND USE OF THE SAME | Japan Tobacco Inc. (JP) | 1998-06-24 | — | — | EP | disclosed |
| EP-0835248-A1 | 1-AMINO-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1998-04-15 | — | — | EP | disclosed |
| US-5691319-A | ANTICARCINOGENIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| WO-1997035845-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-02 | — | — | WO | disclosed |
| WO-1997001543-A1 | 1-AMINO-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-01-16 | — | — | WO | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |