⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713050 | 0.92 | — | — | |
| SCHEMBL7424126 | 0.89 | — | — | |
| SCHEMBL2529651 | 0.89 | — | — | |
| SCHEMBL2529565 | 0.89 | — | — | |
| SCHEMBL194152 | 0.81 | — | — | |
| SCHEMBL10717480 | 0.81 | MAPK1 (0.36) | — | |
| SCHEMBL10932413 | 0.81 | MAPK1 (0.36) | — | |
| SCHEMBL8888918 | 0.79 | — | — | |
| SCHEMBL12361992 | 0.78 | MAPK1 (0.35) | — | |
| SCHEMBL19193963 | 0.78 | MAPK1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |
| EP-3737670-A1 | BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2020-11-18 | — | — | EP | disclosed |
| US-20200331866-A1 | BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2020-10-22 | — | — | US | disclosed |
| US-20200283439-A1 | TRICYCLIC QUINOLINE AND QUINOXALINE DERIVATIVES | AbbVie Deutschland GmbH & Co. KG (DE) | 2020-09-10 | — | — | US | disclosed |
| CN-111566096-A | Benzamide compounds and their use as herbicides | 巴斯夫欧洲公司 | 2020-08-21 | — | — | CN | disclosed |
| EP-3317271-B1 | INHIBITORS OF EZH2 (ENHANCER OF ZESTE HOMOLOG 2) | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2020-05-13 | — | — | EP | disclosed |
| WO-2019162308-A1 | BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2019-08-29 | — | — | WO | disclosed |
| WO-2019162309-A1 | BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2019-08-29 | — | — | WO | disclosed |
| WO-2019134993-A1 | BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2019-07-11 | — | — | WO | disclosed |
| US-20190071443-A1 | TRICYCLIC QUINOLINE AND QUINOXALINE DERIVATIVES | AbbVie Deutschland GmbH & Co. KG (DE) | 2019-03-07 | — | — | US | disclosed |
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| WO-1996021645-A1 | SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1996-07-18 | — | — | WO | disclosed |
| EP-0569592-A1 | CARBOSTYRIL DERIVATIVE AND PLATELET AGGLUTINATION INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-18 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |
| US-4532239-A | N-phenoxypropanol-N'-pyridazinyl ethylendiamines as β-receptor blockers | CASSELLA AKTIENGESELLSCHAFT (DE) | 1985-07-30 | — | — | US | disclosed |
| EP-0054946-B1 | BASIC SUBSTITUTED PYRIDAZINES, THEIR PREPARATION AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1984-08-15 | — | — | EP | disclosed |
| EP-0054946-A1 | Basic substituted pyridazines, their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1982-06-30 | — | — | EP | disclosed |
| US-4216314-A | CARDIOSELECTIVE B-ADRENOLYTIC AGENTS, ANTIARRHYTHMIC AGENTS AND HYPOTENSIVE AGENTS | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DE) | 1980-08-05 | — | — | US | disclosed |