Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 8/20 | 0.43 |
| ▸ | IL1B | P01584 | 8/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25296220 | 1.00 | NLRP3 (0.43) | NLRP3IL1BKAT2BBTKEGFR | |
| SCHEMBL30488565 | 1.00 | NLRP3 (0.43) | NLRP3IL1BKAT2BBTKEGFR | |
| SCHEMBL25255243 | 0.91 | NLRP3 (0.51) | NLRP3IL1BKAT2BEGFREHMT2 | |
| SCHEMBL25296315 | 0.91 | NLRP3 (0.51) | NLRP3IL1BKAT2BEGFREHMT2 | |
| SCHEMBL30488465 | 0.87 | NLRP3 (0.42) | NLRP3IL1BKAT2BBTKEGFR | |
| SCHEMBL30488508 | 0.85 | NLRP3 (0.56) | NLRP3IL1B | |
| SCHEMBL25261360 | 0.85 | NLRP3 (0.56) | NLRP3IL1B | |
| SCHEMBL25299333 | 0.85 | NLRP3 (0.56) | NLRP3IL1B | |
| SCHEMBL25302271 | 0.84 | NLRP3 (0.45) | NLRP3IL1BEHMT2 | |
| SCHEMBL25302275 | 0.84 | NLRP3 (0.45) | NLRP3IL1BEHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |