Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FPR3 | P25089 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25301779 | 0.91 | KDM4E (0.42) | GPR119KDM4EPKMADORA2AADORA2B | |
| SCHEMBL31270804 | 0.91 | KDM4E (0.42) | GPR119KDM4EPKMADORA2AADORA2B | |
| SCHEMBL29030555 | 0.88 | NPC1 (0.37) | KDM4EADORA2AMAPTPDE4APDE4B | |
| SCHEMBL31025948 | 0.86 | GRIN2B (0.55) | — | |
| SCHEMBL25254475 | 0.86 | GRIN2B (0.55) | — | |
| SCHEMBL25301684 | 0.82 | NPC1 (0.38) | ADORA2AADORA2BMAPTPDE4APDE4B | |
| SCHEMBL31270846 | 0.82 | KDM4E (0.48) | GPR119KDM4EPKMADORA2AADORA2B | |
| SCHEMBL25255284 | 0.82 | KDM4E (0.48) | GPR119KDM4EPKMADORA2AADORA2B | |
| SCHEMBL25818351 | 0.81 | NPC1 (0.35) | KDM4EADORA2AADORA2BMAPTPDE4A | |
| SCHEMBL25295149 | 0.79 | KDM4E (0.43) | GPR119KDM4EPKMADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125121-A1 | TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |
| WO-2023125121-A1 | TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |