Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 18/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31025948 | 1.00 | GRIN2B (0.55) | GRIN2BCYP2D6CYP2C9CYP3A4MEN1 | |
| SCHEMBL29030555 | 0.87 | NPC1 (0.37) | GRIN2BCYP2C9MEN1LMNAKMT2A | |
| SCHEMBL25299136 | 0.86 | GPR119 (0.43) | — | |
| SCHEMBL31025943 | 0.83 | GRIN2B (0.65) | GRIN2BCYP2D6CYP2C9CYP3A4 | |
| SCHEMBL25256028 | 0.83 | GRIN2B (0.65) | GRIN2BCYP2D6CYP2C9CYP3A4 | |
| SCHEMBL25301684 | 0.80 | NPC1 (0.38) | CYP2C9 | |
| SCHEMBL31270671 | 0.80 | GRIN2B (0.60) | GRIN2BCYP2D6CYP2C9CYP3A4 | |
| SCHEMBL25253285 | 0.80 | GRIN2B (0.60) | GRIN2BCYP2D6CYP2C9CYP3A4 | |
| SCHEMBL25294483 | 0.79 | GRIN2B (0.38) | GRIN2BCYP2D6CYP2C9CYP3A4MEN1 | |
| SCHEMBL25301779 | 0.77 | KDM4E (0.42) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023207710-A1 | ANTIBODY-DRUG CONJUGATE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-11-02 | — | — | WO | disclosed |
| WO-2023125121-A1 | TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |