SCHEMBL25299366

SCHEMBL25299366

CCCCCCC[Si](OC(C)C)(OC(C)C)OC(C)C

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
DNM1 Q05193 2/20 0.33
TRPM8 Q7Z2W7 4/20 0.32
OPRM1 P35372 1/20 0.32
EPHX1 P07099 1/20 0.31
LPAR2 Q9HBW0 3/20 0.31
LPAR3 Q9UBY5 3/20 0.31
SPHK1 Q9NYA1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL185532 1.00 LMNA (0.39) LMNATSHRTHRBDNM1TRPM8
SCHEMBL190922 1.00 LMNA (0.39) LMNATSHRTHRBDNM1TRPM8
SCHEMBL16238303 1.00 LMNA (0.39) LMNATSHRTHRBDNM1TRPM8
SCHEMBL958168 1.00 LMNA (0.39) LMNATSHRTHRBDNM1TRPM8
SCHEMBL28997508 1.00 LMNA (0.39) LMNATSHRTHRBDNM1TRPM8
SCHEMBL25261552 1.00 LMNA (0.39) LMNATSHRTHRBDNM1TRPM8
SCHEMBL191086 1.00 LMNA (0.39) LMNATSHRTHRBDNM1TRPM8
SCHEMBL25263781 1.00 LMNA (0.39) LMNATSHRTHRBDNM1TRPM8
SCHEMBL2400694 0.98 LMNA (0.36) LMNATSHRTHRBTRPM8OPRM1
SCHEMBL108991 0.90 LMNA (0.33) LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4208509-B1 CROSS-LINKABLE COMPOSITIONS BASED ON ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2024-02-28 EP disclosed
US-20230235174-A1 CROSS-LINKABLE COMPOSITIONS BASED ON ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2023-07-27 US disclosed
EP-4208509-A1 CROSS-LINKABLE COMPOSITIONS BASED ON ORGANOSILICON COMPOUNDS Wacker Chemie AG (DE) 2023-07-12 EP disclosed
WO-2022048730-A1 CROSS-LINKABLE COMPOSITIONS BASED ON ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2022-03-10 WO disclosed
CN-111233916-A Long carbon chain sulfur-containing silane coupling agent, and preparation method and application thereof 南京曙光精细化工有限公司 2020-06-05 CN disclosed