SCHEMBL2530002

SCHEMBL2530002

c1ccc([SiH2]C(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.39
F2 P00734 1/20 0.39
TSHR P16473 1/20 0.39
TAAR1 Q96RJ0 4/20 0.37
HTR2A P28223 1/20 0.36
CYP2D6 P10635 1/20 0.35
SRC P12931 1/20 0.35
LMNA P02545 2/20 0.33
HRH1 P35367 1/20 0.33
MTOR P42345 1/20 0.33
RAB9A P51151 1/20 0.33
GRM7 Q14831 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7889952 0.84 DPP4 (0.32) DPP4F2TSHRTAAR1HTR2A
SCHEMBL9140660 0.79 CFTR (0.52) CYP2D6
SCHEMBL28853373 0.77 CHRNB2 (0.33)
SCHEMBL3817688 0.76
SCHEMBL8386068 0.74 DPP4 (0.41) DPP4F2TSHRTAAR1HTR2A
SCHEMBL4774509 0.73 DPP4 (0.45) DPP4F2TSHRTAAR1HTR2A
SCHEMBL5420712 0.73 MAPT (0.35) DPP4F2TSHRTAAR1LMNA
SCHEMBL1494253 0.71 DPP4 (0.43) DPP4F2TSHRTAAR1HTR2A
SCHEMBL842216 0.71 DPP4 (0.43) DPP4F2TSHRTAAR1HTR2A
SCHEMBL23532355 0.70 DPP4 (0.33) DPP4F2TSHRTAAR1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9890231-B2 Triarylphosphine or triarylarsine compound, alpha-olefin polymerization catalyst using the compound, ternary copolymer, and production process of alpha-olefin-((meth)acrylic acid)-based copolymer JAPAN POLYETHYLENE CORPORATION (JP) 2018-02-13 US disclosed
US-20160264699-A1 NOVEL TRIARYLPHOSPHINE OR TRIARYLARSINE COMPOUND, ALPHA-OLEFIN POLYMERIZATION CATALYST USING THE COMPOUND, TERNARY COPOLYMER, AND PRODUCTION PROCESS OF ALPHA-OLEFIN -((METH)ACRYLIC ACID)-BASED COPOLYMER JAPAN POLYETHYLENE CORPORATION (JP) 2016-09-15 US disclosed
US-9376459-B2 Triarylphosphine or triarylarsine compound, alpha-olefin polymerization catalyst using the compound, ternary copolymer, and production process of alpha-olefin-((meth)acrylic acid)-based copolymer JAPAN POLYETHYLENE CORPORATION (JP) 2016-06-28 US disclosed
US-20110257351-A1 NOVEL TRIARYLPHOSPHINE OR TRIARYLARSINE COMPOUND, ALPHA-OLEFIN POLYMERIZATION CATALYST USING THE COMPOUND, TERNARY COPOLYMER, AND PRODUCTION PROCESS OF ALPHA-OLEFIN -((METH)ACRYLIC ACID)-BASED COPOLYMER JAPAN POLYPROPYLENE CORPORATION (JP) 2011-10-20 US disclosed
US-7659005-B2 Label can be attached to product having high temperatures during high-temperature treatment or immediately after treatment; employs as sticking layer a hardened coating film including a silicone resin and a polymetallocarbosilane resin, zinc powder, tin powder, and aluminum powder YUSHI-SEIHIN CO., LTD. (JP) 2010-02-09 US disclosed
US-20070027241-A1 Heat-resistant label applicable at high temperature YUSHI-SEIHIN CO., LTD. (JP) 2007-02-01 US disclosed
EP-1659162-A1 HEAT-RESISTANT LABEL APPLICABLE AT HIGH TEMPERATURE Yushi-Seihin Co., Ltd. (JP) 2006-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110257351-A1 NOVEL TRIARYLPHOSPHINE OR TRIARYLARSINE COMPOUND, ALPHA-OLEFIN POLYMERIZATION CATALYST USING THE COMPOUND, TERNARY COPOLYMER, AND PRODUCTION PROCESS OF ALPHA-OLEFIN -((METH)ACRYLIC ACID)-BASED COPOLYMER AS3MT, ATR, ALK DPP4 4844/4885F2 2445/4885TSHR 621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.