Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL2530225

N.N.O=C(OCCCCCCOC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.92

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.92
LMNA P02545 4/20 0.66
MAPK1 P28482 1/20 0.57
HIF1A Q16665 1/20 0.57
SLC6A2 P23975 1/20 0.57
SLC6A3 Q01959 1/20 0.57
KMT2A Q03164 1/20 0.57
ALDH1A1 P00352 3/20 0.55
TSHR P16473 1/20 0.55
NPC1 O15118 1/20 0.54
MAPT P10636 1/20 0.54
RAB9A P51151 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.53
F2 P00734 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11896606 0.98 TDP1 (0.96) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL11896235 0.98 TDP1 (0.96) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL2069111 0.98 TDP1 (0.96) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL17466182 0.98 TDP1 (0.96) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL223238 0.98 TDP1 (0.96) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL225815 0.98 TDP1 (0.96) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL223441 0.96 TDP1 (1.00) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL416566 0.91 TDP1 (0.91) TDP1LMNAMAPK1HIF1ASLC6A2
Ammonia Solution, Strong SCHEMBL25372858 0.91 TDP1 (0.76) TDP1LMNAMAPK1ALDH1A1TSHR
Ammonia Solution, Strong SCHEMBL28458691 0.91 TDP1 (0.76) TDP1LMNAMAPK1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2392599-B1 HIGHLY SATURATED COPOLYMER RUBBER CONTAINING NITRILE GROUPS ZEON CORP (JP) 2022-05-04 EP disclosed
CN-104854183-B Nitrile rubber composition and rubber crosslinked material 日本瑞翁株式会社 2019-08-20 CN disclosed
CN-105873995-B Nitrile-the butadiene rubber and its production method of stable storing 阿朗新科德国有限责任公司 2019-06-21 CN disclosed
CN-105849169-B Phenol-containing hydrogenated nitrile rubber 阿朗新科德国有限责任公司 2019-05-28 CN disclosed
US-10280244-B2 Nitrile group-containing copolymer rubber, cross-linkable rubber composition, and cross-linked rubber ZEON CORPORATION (JP) 2019-05-07 US disclosed
CN-105102486-B Nitrile group-containing copolymer rubber, crosslinkable rubber composition, and crosslinked rubber product 日本瑞翁株式会社 2018-12-28 CN disclosed
EP-2239297-B1 CROSSLINKABLE NITRILE RUBBER COMPOSITION AND CROSSLINKED RUBBER ZEON CORP (JP) 2018-12-26 EP disclosed
CN-105992797-B Phenol-containing hydrogenated nitrile rubber 阿朗新科德国有限责任公司 2018-11-16 CN disclosed
CN-105764941-B Functionalized copolymer rubber containing nitrile groups 阿朗新科德国有限责任公司 2018-08-14 CN disclosed
US-10030107-B2 Crosslinking rubber composition and crosslinked rubber production method ZEON CORPORATION (JP) 2018-07-24 US disclosed
CN-103403034-B Functionalized nitrile rubber and preparation thereof LANXESS DEUTSCHLAND GMBH (DE) 2016-05-04 CN disclosed
EP-2660285-A1 RUBBER COMPOSITION AND CROSSLINKED RUBBER PRODUCT Zeon Corporation (JP) 2013-11-06 EP disclosed
US-20130280459-A1 RUBBER COMPOSITION AND CROSS-LINKED RUBBER ZEON CORPORATION (JP) 2013-10-24 US disclosed
US-8372918-B2 Nitrile group-containing highly saturated copolymer rubber ZEON CORPORATION (JP) 2013-02-12 US disclosed
CN-102481561-A Metathesis of nitrile rubbers in the presence of transition metal catalysts LANXESS DEUTSCHLAND GMBH 2012-05-30 CN disclosed
US-20110301300-A1 NITRILE GROUP-CONTAINING HIGHLY SATURATED COPOLYMER RUBBER ZEON CORPORATION (JP) 2011-12-08 US disclosed
EP-2392599-A1 HIGHLY SATURATED COPOLYMER RUBBER CONTAINING NITRILE GROUPS Zeon Corporation (JP) 2011-12-07 EP disclosed
US-8034881-B2 Cross-linkable nitrile rubber composition and cross-linked rubber ZEON CORPORATION (JP) 2011-10-11 US disclosed
EP-2239297-A1 CROSSLINKABLE NITRILE RUBBER COMPOSITION AND CROSSLINKED RUBBER Zeon Corporation (JP) 2010-10-13 EP disclosed
US-20100256294-A1 CROSS-LINKABLE NITRILE RUBBER COMPOSITION AND CROSS-LINKED RUBBER ZEON CORPORATION (JP) 2010-10-07 US disclosed