⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3435783 | 0.77 | — | — | |
| SCHEMBL19844923 | 0.74 | TSHR (0.30) | — | |
| SCHEMBL23575323 | 0.72 | — | — | |
| SCHEMBL21896695 | 0.72 | — | — | |
| SCHEMBL3480700 | 0.72 | — | — | |
| SCHEMBL7592451 | 0.71 | — | — | |
| SCHEMBL3480638 | 0.69 | — | — | |
| SCHEMBL6267318 | 0.67 | LMNA (0.39) | — | |
| SCHEMBL7073610 | 0.67 | — | — | |
| SCHEMBL2030023 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3141554-B1 | SILICONE HAVING A BIS(TRIALKYLSILYL)AMINOPROPYL GROUP AT ONE TERMINAL | SHINETSU CHEMICAL CO (JP) | 2018-01-03 | — | — | EP | disclosed |
| US-20170073473-A1 | SILICONE HAVING A BIS(TRIALKYLSILYL) AMINOPROPYL GROUP AT ONE TERMINAL | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-03-16 | — | — | US | disclosed |
| EP-3141554-A1 | SILICONE HAVING A BIS(TRIALKYLSILYL)AMINOPROPYL GROUP AT ONE TERMINAL | Shin-Etsu Chemical Co., Ltd. (JP) | 2017-03-15 | — | — | EP | disclosed |
| EP-2411400-B1 | PROCESS FOR THE SYNTHESIS OF 1,3-BIS(AMINOALKYL)DISILOXANES | WACKER CHEMIE AG (DE) | 2012-09-05 | — | — | EP | disclosed |
| US-20120004436-A1 | PROCESS FOR THE SYNTHESIS OF 1,3-BIS(AMINOALKYL)DISILOXANES | WACKER CHEMIE AG (DE) | 2012-01-05 | — | — | US | disclosed |