Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25313157 | 1.00 | TAAR1 (0.54) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL25314071 | 0.90 | TAAR1 (0.54) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL25314069 | 0.90 | TAAR1 (0.54) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL25901210 | 0.90 | TAAR1 (0.54) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL25900640 | 0.90 | TAAR1 (0.54) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL25901212 | 0.88 | TAAR1 (0.52) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL25900620 | 0.88 | TAAR1 (0.52) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL25900937 | 0.88 | TAAR1 (0.50) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL25905937 | 0.87 | TAAR1 (0.51) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL25900938 | 0.87 | TAAR1 (0.48) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250026731-A1 | PRODRUGS OF MDMA, MDA, AND DERIVATIVES THEREOF | EMPATHBIO INC (US) | 2025-01-23 | — | — | US | disclosed |
| US-11845736-B2 | Prodrugs of MDMA, MDA, and derivatives thereof | EMPATHBIO, INC. (US) | 2023-12-19 | — | — | US | disclosed |
| WO-2023137446-A1 | PRODRUGS OF 3,4-METHYLENEDIOXY- N-ETHYL-AMPHETAMINE (MDEA) AND USES THEREOF | TERRAN BIOSCIENCES INC. (US) | 2023-07-20 | — | — | WO | disclosed |
| US-20230227420-A1 | PRODRUGS OF MDMA, MDA, AND DERIVATIVES THEREOF | EMPATHBIO, INC. | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11845736-B2 | Prodrugs of MDMA, MDA, and derivatives thereof | COMT, PNMT, ABCB1 | TAAR1 120/4885SLC6A4 29/4885SLC6A2 41/4885 |
| US-20230227420-A1 | PRODRUGS OF MDMA, MDA, AND DERIVATIVES THEREOF | COMT, PNMT, ABCB1 | TAAR1 120/4885SLC6A4 29/4885SLC6A2 41/4885 |
| US-20250026731-A1 | PRODRUGS OF MDMA, MDA, AND DERIVATIVES THEREOF | COMT, PNMT, ABCB1 | TAAR1 120/4885SLC6A4 29/4885SLC6A2 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.