Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25309723 | 0.90 | KMT2A (0.48) | KMT2AMEN1SLC2A1SLC2A4THRB | |
| SCHEMBL25307755 | 0.81 | KMT2A (0.41) | KMT2AMEN1THRBMAPTPOLB | |
| SCHEMBL25308360 | 0.79 | KMT2A (0.46) | KMT2AMEN1THRBMAPTPOLB | |
| SCHEMBL25308514 | 0.79 | KMT2A (0.57) | KMT2AMEN1THRBMAPTPOLB | |
| SCHEMBL25309554 | 0.77 | KMT2A (0.46) | KMT2AMEN1THRBMAPTPOLB | |
| SCHEMBL6726742 | 0.75 | KMT2A (0.50) | KMT2AMEN1MAPTKDM4EKCNQ3 | |
| SCHEMBL25311726 | 0.74 | KMT2A (0.41) | KMT2AMEN1THRBMAPTPOLB | |
| SCHEMBL25308546 | 0.73 | KMT2A (0.57) | KMT2AMEN1SLC2A1SLC2A4THRB | |
| SCHEMBL29639224 | 0.72 | SMN1; SMN2 (0.52) | KMT2AMEN1SLC2A1SLC2A4MAPT | |
| SCHEMBL25309190 | 0.71 | NPC1 (0.45) | KMT2AMEN1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134708-A1 | THIAZOLOPYRIDYL AMIDE DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | BEIGENE , LTD. (KY) | 2023-07-20 | — | — | WO | disclosed |