Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25309723 | 0.83 | KMT2A (0.48) | KMT2AATMALDH1A1SLC2A1SLC2A4 | |
| SCHEMBL29040095 | 0.82 | KMT2A (0.54) | KMT2AATMALDH1A1MAPTHSD17B10 | |
| SCHEMBL30304968 | 0.80 | KMT2A (0.72) | KMT2AATMALDH1A1MAPTHSD17B10 | |
| SCHEMBL29855615 | 0.80 | KMT2A (0.72) | KMT2AATMALDH1A1MAPTHSD17B10 | |
| SCHEMBL28386352 | 0.80 | KMT2A (0.65) | KMT2AATMALDH1A1MAPTCYP1A2 | |
| SCHEMBL29936263 | 0.79 | KMT2A (0.60) | KMT2AATMALDH1A1MAPTHSD17B10 | |
| SCHEMBL10001382 | 0.79 | KMT2A (0.60) | KMT2AATMALDH1A1MAPTHSD17B10 | |
| SCHEMBL21963607 | 0.77 | ALDH1A1 (0.68) | KMT2AALDH1A1MAPTHSD17B10CYP1A2 | |
| SCHEMBL25263346 | 0.75 | MAPT (0.64) | ALDH1A1MAPTLMNAKDM4EMAPK1 | |
| SCHEMBL15247099 | 0.75 | KMT2A (0.55) | KMT2AATMALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134708-A1 | THIAZOLOPYRIDYL AMIDE DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | BEIGENE , LTD. (KY) | 2023-07-20 | — | — | WO | disclosed |