Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924675 | 0.96 | ALDH1A1 (0.52) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL8926214 | 0.96 | ALDH1A1 (0.52) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL20240559 | 0.94 | ALDH1A1 (0.50) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL23929290 | 0.94 | TSHR (0.44) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL23929282 | 0.94 | TSHR (0.44) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL22288099 | 0.90 | TSHR (0.59) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL8925139 | 0.86 | TSHR (0.48) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL28435606 | 0.86 | TSHR (0.65) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL12179851 | 0.86 | HTT (0.54) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL5795824 | 0.86 | HTT (0.54) | TSHRALDH1A1MEN1THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134712-A1 | ANTIDIABETIC COMPOUNDS AND COMPOSITIONS | REZUBIO PHARMACEUTICALS CO., LTD (CN) | 2023-07-20 | — | — | WO | disclosed |