SCHEMBL25308445

SCHEMBL25308445

COc1c(C2CN(C(=O)OC(C)(C)C)C2)ccnc1F

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ ALOX5AP P20292 4/20 0.44
▸ FEN1 P39748 4/20 0.44
▸ CCNT1 O60563 5/20 0.43
▸ CDK9 P50750 5/20 0.43
▸ KDM4E B2RXH2 1/20 0.42
▸ GPR119 Q8TDV5 3/20 0.40
▸ PDE4B Q07343 2/20 0.39
▸ GPBAR1 Q8TDU6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25308545 0.83 GPR119 (0.44) ALOX5APFEN1CCNT1CDK9KDM4E
SCHEMBL2596096 0.81 POLB (0.47) ALOX5APFEN1KDM4EGPR119
SCHEMBL31654894 0.81 CCNT1 (0.45) CCNT1CDK9PDE4BGPBAR1
SCHEMBL25888787 0.81 CCNT1 (0.45) CCNT1CDK9PDE4BGPBAR1
SCHEMBL31655123 0.78 KDM4E (0.41) ALOX5APFEN1CCNT1CDK9KDM4E
SCHEMBL25888628 0.78 KDM4E (0.41) ALOX5APFEN1CCNT1CDK9KDM4E
SCHEMBL25888712 0.77 PDE10A (0.49) ALOX5APFEN1KDM4EGPR119
SCHEMBL31655333 0.77 PDE10A (0.49) ALOX5APFEN1KDM4EGPR119
SCHEMBL30527491 0.77 GPR119 (0.43) ALOX5APFEN1KDM4EGPR119PDE4B
SCHEMBL25306675 0.77 GPR119 (0.43) ALOX5APFEN1KDM4EGPR119PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215029-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 — — US disclosed
EP-4463459-A1 STAT MODULATORS AND USES THEREOF Recludix Pharma, Inc. (US) 2024-11-20 — — EP disclosed
CN-118804917-A STAT modulators and uses thereof 瑞克鲁迪克斯制药股份有限公司 2024-10-18 — — CN disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 — — WO disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215029-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A ALOX5AP 2453/4885FEN1 4852/4885CCNT1 2276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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