SCHEMBL25308488

SCHEMBL25308488

COc1ccc([PH](c2ccc(OC)cc2)(c2ccc(OC)cc2)[PH](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.59
LTA4H P09960 2/20 0.56
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA12 O43570 1/20 0.52
CA14 Q9ULX7 1/20 0.52
TRPA1 O75762 1/20 0.50
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
OPRM1 P35372 1/20 0.46
OPRL1 P41146 1/20 0.46
ACHE P22303 1/20 0.44
CYP1A2 P05177 2/20 0.43
CYP2A6 P11509 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
ALDH1A1 P00352 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21694302 0.86 CA4 (0.59) CA4LTA4HCA1CA2CA7
Bromide SCHEMBL29266596 0.84 CA4 (0.56) CA4LTA4HCA1CA2CA7
SCHEMBL6470447 0.82 CA4 (0.54) CA4LTA4HCA1CA2CA7
SCHEMBL8780771 0.81 ACHE (0.71) CA1CA2CA7CA9CA12
SCHEMBL6816521 0.80 CA4 (0.52) CA4LTA4HCA1CA2CA7
SCHEMBL16771210 0.80 CA4 (0.52) CA4LTA4HCA1CA2CA7
Anisole SCHEMBL30601749 0.76
Anisole SCHEMBL28813915 0.76 CA4 (1.00) CA4LTA4HCA1CA2CA7
Anisole SCHEMBL20328417 0.76
Anisole SCHEMBL8472521 0.76 CA4 (1.00) CA4LTA4HCA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023137133-A2 PROCESS FOR THE SELECTIVE CATALYTIC HYDROGENATION OF DIENONES BASF SE (DE) 2023-07-20 WO disclosed