Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2532643 | 0.94 | KMT2A (0.42) | KMT2AADRB3HPGDBACE1 | |
| SCHEMBL2526823 | 0.91 | AOC3 (0.43) | KMT2ATDP1 | |
| SCHEMBL2529626 | 0.89 | KMT2A (0.40) | KMT2AADRB3HPGDBACE1TDP1 | |
| SCHEMBL2531063 | 0.88 | AKR1C3 (0.37) | KMT2ABACE1 | |
| SCHEMBL2532007 | 0.85 | BCL9 (0.41) | KMT2ABACE1 | |
| SCHEMBL2529496 | 0.84 | KMT2A (0.37) | KMT2A | |
| SCHEMBL2529281 | 0.83 | ESR1 (0.49) | KMT2A | |
| SCHEMBL2525190 | 0.83 | KMT2A (0.41) | KMT2A | |
| SCHEMBL2525241 | 0.82 | KMT2A (0.51) | KMT2ABACE1TDP1 | |
| SCHEMBL2525540 | 0.82 | PPARG (0.41) | KMT2AADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | disclosed |
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | HRH1, HRH3, HRH2 | KMT2A 2317/4885ADRB3 557/4885HPGD 1523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.