Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2528951 | 0.90 | L3MBTL1 (0.42) | KMT2APPARGPPARAL3MBTL1ATM | |
| SCHEMBL2527548 | 0.90 | KMT2A (0.46) | KMT2APPARGPPARAL3MBTL1ATM | |
| SCHEMBL2527448 | 0.90 | KMT2A (0.41) | KMT2APPARGPPARASMN1; SMN2KDM4E | |
| SCHEMBL2531907 | 0.89 | TAAR1 (0.42) | PPARGPPARABACE1L3MBTL1 | |
| SCHEMBL2530998 | 0.89 | KMT2A (0.49) | KMT2AHPGDBACE1ADRB3TDP1 | |
| SCHEMBL2526376 | 0.89 | KMT2A (0.46) | KMT2APPARGPPARAL3MBTL1ATM | |
| SCHEMBL2526417 | 0.89 | KMT2A (0.46) | KMT2APPARGPPARAMEN1TSHR | |
| SCHEMBL2530995 | 0.89 | PPARG (0.39) | KMT2APPARGPPARASMN1; SMN2MEN1 | |
| SCHEMBL2529210 | 0.89 | KMT2A (0.40) | KMT2APPARGPPARAMEN1L3MBTL1 | |
| SCHEMBL2527784 | 0.88 | PPARG (0.43) | KMT2APPARGPPARAADRB3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | disclosed |
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | HRH1, HRH3, HRH2 | KMT2A 2317/4885HPGD 1523/4885CYP19A1 3348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.