Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24962301 | 0.93 | GPR119 (0.57) | GPR119RORCLIPEMAPTSTS | |
| SCHEMBL31713185 | 0.86 | GPR119 (0.57) | GPR119RORCLIPEMAPTSTS | |
| SCHEMBL30510788 | 0.81 | GPR119 (0.58) | GPR119HSD11B1 | |
| SCHEMBL25309274 | 0.81 | GPR119 (0.52) | GPR119HSD11B1EIF2AK4 | |
| SCHEMBL30859784 | 0.80 | GPR119 (0.50) | GPR119MAPT | |
| SCHEMBL22777328 | 0.78 | GPR119 (0.59) | GPR119NR1H2PIK3R1PIK3CA | |
| SCHEMBL21521091 | 0.77 | GPR119 (0.60) | GPR119MAPT | |
| SCHEMBL31381882 | 0.77 | GPR119 (0.52) | GPR119 | |
| SCHEMBL31271175 | 0.77 | GPR119 (0.58) | GPR119 | |
| SCHEMBL26126417 | 0.77 | MAPT (0.45) | GPR119RORCLIPEMAPTSTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139536-A1 | (4-PIPERAZIN-1YL)-4-ALKYL-PHTHALAZIN-1(2H)-ONE COMPOUNDS AS PARP7 INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-07-27 | — | — | WO | disclosed |