Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK5 | P34947 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25310993 | 1.00 | GRK5 (1.00) | GRK5 | |
| SCHEMBL25310995 | 1.00 | GRK5 (1.00) | GRK5 | |
| SCHEMBL30375960 | 0.93 | GRK5 (1.00) | GRK5 | |
| SCHEMBL25311570 | 0.89 | GRK5 (1.00) | GRK5 | |
| SCHEMBL25311573 | 0.89 | GRK5 (1.00) | GRK5 | |
| SCHEMBL25311565 | 0.89 | GRK5 (1.00) | GRK5 | |
| SCHEMBL16490729 | 0.89 | GRK5 (0.79) | GRK5 | |
| SCHEMBL16490701 | 0.89 | GRK5 (0.79) | GRK5 | |
| SCHEMBL16486565 | 0.89 | GRK5 (0.79) | GRK5 | |
| SCHEMBL16568055 | 0.89 | GRK5 (0.79) | GRK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212120-A1 | SMALL MOLECULE INHIBITORS OF GRK5 AND GRK5 SUBFAMILY MEMBERS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212120-A1 | SMALL MOLECULE INHIBITORS OF GRK5 AND GRK5 SUBFAMILY MEMBERS AND USES THEREOF | GRK5, GRK3, GRK4 | GRK5 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.