Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK5 | P34947 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25310990 | 0.93 | GRK5 (1.00) | GRK5 | |
| SCHEMBL25310993 | 0.93 | GRK5 (1.00) | GRK5 | |
| SCHEMBL25310995 | 0.93 | GRK5 (1.00) | GRK5 | |
| SCHEMBL25311992 | 0.89 | GRK5 (1.00) | GRK5 | |
| SCHEMBL25311986 | 0.89 | GRK5 (1.00) | GRK5 | |
| SCHEMBL25311991 | 0.89 | GRK5 (1.00) | GRK5 | |
| SCHEMBL25311040 | 0.87 | GRK5 (1.00) | GRK5 | |
| SCHEMBL25311031 | 0.87 | GRK5 (1.00) | GRK5 | |
| SCHEMBL16466799 | 0.87 | GRK5 (1.00) | GRK5 | |
| SCHEMBL16466800 | 0.87 | GRK5 (1.00) | GRK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4157858-A2 | SMALL MOLECULE INHIBITORS OF GRK5 AND GRK5 SUBFAMILY MEMBERS AND USES THEREOF | The Regents of The University of Michigan (US) | 2023-04-05 | — | — | EP | disclosed |